Alli tablet.
TrustScore 4.9/5107 reviewsAlli — branded orlistat at the gentler 60 mg dose — blocks around a quarter of the fat you eat, working in your gut rather than on your appetite. A needle-free capsule, supplied where clinically appropriate.
Alli with PPRX — the private prescription, clinical review and free next-day delivery are all part of one price.
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for the 60 mg × 84 capsules dose · per pack · about four weeks
You save £10 on every order
Includes prescription, clinical review & delivery · Subject to clinical consultation
Alli is the original branded version of orlistat at the lower 60 mg dose. It works the same way as prescription-strength orlistat — blocking the enzymes that digest dietary fat so around a quarter of the fat you eat passes through unabsorbed — just with a lighter touch, which many people find gentler on the gut.
It's a capsule taken with each main meal, up to three a day, alongside a reduced-calorie, lower-fat diet. In its registration trials, people taking Alli lost roughly twice as much weight over six months as those dieting alone. It's intended as a shorter-term aid: progress is reviewed at 12 weeks, and treatment shouldn't run beyond six months.
Active ingredient
Orlistat (60 mg)
Class
Lipase inhibitor
Cadence
With main meals
Dose range
60 mg
Form
Oral capsule
From
£64.99 / mo
How Alli works.
Alli works in your gut, not your brain — the 60 mg dose stops around a quarter of the fat in your food from ever being absorbed.
orlistat 60 mg
up to 3× daily tablet
Blocks the digestive enzymes that break down dietary fat, so around a quarter passes through unabsorbed.
Unabsorbed fat means unabsorbed calories, so every meal effectively gets lighter — without acting on appetite hormones. The lower dose blocks a little less fat than orlistat 120 mg, and tends to be gentler on the digestion for it.
Honest about side effects.
Side effects come from the fat Alli blocks leaving the body, and the 60 mg dose is the gentler option — keeping each meal below roughly 15 g of fat prevents most of them. A bedtime multivitamin covers vitamins A, D, E and K, and your pharmacist is a message away.
Common & usually mild
- Oily or fatty stools
- Needing the toilet urgently
- Wind, with or without oily spotting
- Stomach pain
- Loose stools
Rare & serious
Rare but serious effects include pancreatitis and rectal bleeding. Seek urgent care for severe, persistent abdominal pain or blood in your stools.
Always read the patient information leaflet. This page is information, not a substitute for the clinical advice you'll receive in your consultation.
Roughly double the weight loss of dieting alone.
Numbers come from the registration trial, not marketing averages — and only ever happen alongside diet, activity and clinical follow-up.
4.4 kg
average loss over six months
24 wks
trial duration
≈ 2×
the loss of diet alone
Registration trials, orlistat 60 mg three times daily vs placebo (4.4 kg vs 2.1 kg), alongside a reduced-calorie diet. Results vary and are more modest than with GLP-1 treatments.
What Alli could mean for you.
Set the slider to where you are today and watch the trial average become actual kilograms — with medication and support, versus the same trial's group who had lifestyle changes alone.
An illustration, not a promise — your prescriber sets real expectations.
98kg
on the trial average, −4.6 kg
One dose, from day one.
There's no ramp-up with Alli — the dose is the same from your first day to your last. What matters is the routine around your meals, and the review that checks it's working for you.
Every day
1 × 60 mg with each main meal
Up to three capsules a day — before, during, or within an hour of eating
Missed a meal?
Skip that capsule
No fat in the meal means nothing for Alli to block
Alongside
A daily multivitamin
Taken at bedtime, to cover fat-soluble vitamins A, D, E and K
Week 12 review
Progress check
If it isn't working for you, treatment is stopped — and it never runs beyond six months
The full price list, up front.
No dose ladder here — one flat price for each option. Each price is per pack (about four weeks of daily tablets) and includes the prescription, clinical review and delivery.
| Dose | Price per pack |
|---|---|
| 60 mg × 84 capsules | £64.99 |
All sales are subject to prescriber approval following a free online consultation.
Prescribed, dispensed, delivered.
One all-in price per pack— the medication, the private prescription, clinical review and free next-day delivery. The consultation is free, and a subscription is optional — Subscribe & Save for £10 off every order, or order one-off.
- Reviewed by a UK-registered prescriber
- Discreet, next day — no needles, no fridge
- Subscribe & Save or order one-off — no lock-in
Subject to clinical consultation
Everything, for one price.
Your Alli price is all-in — the medicine and the care around it, with nothing bolted on afterwards.
Check my eligibility
The genuine medication
Genuine, UK-licensed medicine dispensed by our GPhC-registered UK pharmacy.
Private prescription included
A UK-registered prescriber reviews your consultation before anything is dispensed — the prescription is part of the price.
Clinical review
Every order is checked by our pharmacy team, with ongoing support as your dose changes.
Free next-day delivery
Tracked, discreet packaging, delivered free the next day — no fridge required.
Pharmacist support
Message our pharmacy team whenever you have a question about your treatment.
Your choice of plan
Subscribe & Save for £10 off every order, or order one-off. Pause or cancel anytime.
Alli
questions.
The questions we hear most about Alli. Anything else, write to info@pprx.co.uk.
What's the difference between Alli and orlistat 120 mg?
How much weight can I expect to lose on Alli?
How do I take Alli?
How long can I take Alli for?
Who is Alli suitable for?
Do I need to change how I eat?
From the journal.
Essays from the clinicians who write your prescriptions — explainers, second-look reviews, and the occasional plain-English correction.
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Medically reviewedThis Alli page is reviewed by Omar Kadir, Superintendent Pharmacist, MPharm (GPhC 2078291). For full prescribing and safety information, see the patient information leaflet supplied with your medicine or the electronic medicines compendium.
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free consultation.
Three minutes of your time, reviewed by a UK-registered prescriber. No commitment, no charge for the consultation — and if treatment is approved, free next-day delivery to your door.